منابع مشابه
The ‘terrible Sonnets’ of Gerard Manley Hopkins and the Spirituality of Depression
EPRESSION IS A VERY LONELY DISEASE. Sufferers are unable to see beyond the blackness enclosing them, even if they are surrounded by loving friends and by a supportive family. It is difficult for them to talk to people who do not share their experience, and difficult for those others to understand how they feel. Although there is evidence that depression has been experienced since the earliest t...
متن کاملSUMO wrestling with Ras
This review discusses our current understanding of the small ubiquitin-like modifier (SUMO) pathway and how it functionally intersects with Ras signaling in cancer. The Ras family of small GTPases are frequently mutated in cancer. The role of the SUMO pathway in cancer and in Ras signaling is currently not well understood. Recent studies have shown that the SUMO pathway can both regulate Ras/MA...
متن کاملWrestling with rep exposure
A central methodological problem in programming with multiple levels of abstractions is the loosely defined problem of rep exposure. This paper traces the problem of rep exposure to the precisely defined notion of abstract aliasing. The paper also outlines a statically-enforceable discipline for avoiding abstract aliasing, but the outline is incomplete.
متن کاملSUMO Modification: Wrestling with Protein Conformation
SUMO modification of human thymine-DNA glycosylase facilitates the processing of base excision repair substrates by an unusual mechanism: while leaving the catalytic center unaffected, it induces product release by eliciting a conformational change in the enzyme.
متن کاملDeciding the Undecidable: Wrestling with Hilbert’s Problems
In the year 1900, the German mathematician David Hilbert gave a dramatic address in Paris, at the meeting of the 2nd International Congress of Mathematicians—an address which was to have lasting fame and importance. Hilbert was at that point a rapidly rising star, if not superstar, in mathematics, and before long he was to be ranked with Henri Poincaré as one of the two greatest and most influe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Textual Practice
سال: 2021
ISSN: 0950-236X,1470-1308
DOI: 10.1080/0950236x.2021.1936774